diff --git a/CHANGES b/CHANGES
index b8945e0..af762b4 100644
--- a/CHANGES
+++ b/CHANGES
@@ -1,5 +1,6 @@
 0.9.6 UNRELEASED
  - Fixed typo in package installation section of README
+ - Added more to README about first run with systemd
 
 0.9.5.1 2018-03-10
  - Add conf file location to systemd unit file
diff --git a/README b/README
index 57fce83..2bbee80 100644
--- a/README
+++ b/README
@@ -48,6 +48,14 @@ As an example, using the default dkimpy-user on Debian, the command would be:
 Since /var/run or /run is sometimes on a tempfs, if the PID file directory is
 missing, the milter will create it on startup.
 
+To start dkimpy-milter with systemd for the first time, you will need to take
+the following steps:
+
+[sudo] systemctl daemon-reload
+[sudo] systemctl enable dkimpy-milter
+[sudo] systemctl start dkimpy-milter
+[sudo] systemctl status dkimpy-milter (to verify it started correctly)
+
 As with all milters, dkimpy-milter needs to be integrated with your MTA of
 choice (Sendmail or Postfix).